Allelic structures at hypervariable minisatellite B6.7 in Japanese show population specificity
نویسندگان
چکیده
منابع مشابه
Two hypervariable minisatellite DNA binding proteins.
Hypervariable minisatellite DNA sequences are short, tandemly repeated sequences present at numerous loci in eukaryotes. They stimulate intermolecular homologous recombination up to 13-fold in human cells in culture and may be specific sites for the initiation of recombination in the eukaryotic genome (Wahls, W.P., Wallace, L.J., & Moore, P.D. (1990) Cell 60, 95-103). Reported here is the detec...
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The current study was conducted to consider how pedigree and the gene-dropping analysis can use to monitor genetic diversity, and to recommend a breeding strategy for improving breast weight (BRW) in a population of Japanese quail. A total of 312 birds were divided equally into two lines. One line (S1) was selected for four-week body weight (BW) based on breeding value, and the other (S2) was s...
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The discovery of an anonymous multiallelic locus in 1980 demonstrated for the first time that the human DNA contains hypervariable regions (Wyman & White, 1980). Eight alleles of a polymorphic locus that was not associated with any known gene were identified during the blot hybridization of total human genomic DNA treated with the restrictase EcoRI with a human DNA fragment (16 tbp in length) i...
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Variability in cis-regulation of gene expression has been implicated in the phenotypic manifestation of complex traits including common, multifactorial diseases. The differential expression of alleles due to polymorphism in cis-regulatory elements is common in the human genome, but there is a paucity of information about the context specificity of these control elements. In this study, we exami...
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A minisatellite-binding protein, Msbp-4, with a molecular mass of 35 kDa has been purified from mouse tumor cells that binds to hypervariable Pc-1 and Pc-2 minisatellites. The binding is much more efficient than that to genetically stable minisatellite homologues. As assayed by Southwestern analysis, Msbp-4 favors multiple copies of the Pc-2 repeat sequence GGCAGGA and requires the cytosine-ric...
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ژورنال
عنوان ژورنال: Journal of Human Genetics
سال: 2002
ISSN: 1434-5161,1435-232X
DOI: 10.1007/s100380200031